A study at the University of Minnesota, supported by Achieving Cures Together, indicated Microbiota Transplant Therapy is safe in patients with acute myeloid leukemia and undergoing stem cell transplantation. In the randomized, double blind study, patients enrolled in the active treatment group received microbiota therapeutics after each round of antibiotics. Trial results indicate that patients receiving microbiota transplant therapy had reduced rate of infection compared to patients receiving the placebo, while not statistically significant.
read moreA new study indicates that microbial diversity in the gut is closely related to the severity of the major depressive disorder. Compared to healthy individuals, the abundance of Bacteroides species was significantly increased in participants with moderate and severe depression, while Ruminococcus and Eubacterium were depleted mainly in participants with severe depression.
read moreA recent study demonstrated that the microbiome is altered in patients with Anorexia Nervosa, when compared with healthy individuals. Additionally, when healthy mice received transplanted Anorexia Nervosa stools, initially lost more weight, had slower weight gain and had a higher incidence of appetite suppression genes when compared to mice receiving healthy transplanted stools.
read moreAchieving Cures Together research partner, Dr. Jasmohan Bajaj at the Virginia Commonwealth University’s School of Medicine, in collaboration with Dr. Alexander Khoruts at the University of Minnesota, is studying the link between microbial health, Advanced Liver Disease and alcohol cravings. An early clinical trial demonstrated the safety of microbiota transplant therapy in patients. A new clinical trial aims to investigate the impact of this therapy in a larger group.
read moreACT research partner, Dr. Jasmohan Bajaj, gastroenterologist and liver specialist, is conducting a new clinical trial to better understand how Intestinal Microbiota Transplants can assist patients in overcoming their addiction to alcohol.
read moreFindings suggest that previously unknown species of bacteria is the culprit because is found only in the intestines of people with rheumatoid arthritis. We also found that these bacteria can activate specialized immune cells called T cells in people with rheumatoid arthritis. T cells drive inflammatory responses in the body, and have been linked to the development of different autoimmune diseases.
read moreAntibiotics routinely used in ovarian cancer care indiscriminately kill gut bacteria, leading to faster cancer progression and lower survival rates, according to recent Cleveland Clinic research.
read moreStanford researchers published findings from their study comparing the infant gut microbiome between industrialized and non-industrialized populations. The discovered that more than 20% of the infant microbiome genome of the Hadza people — one of the last groups of true hunter-gathers in the world — represented novel species that are not present in westernized infants, due to dietary and lifestyle differences.
read moreResearchers from the University of Missouri School of Medicine and MU Health Care have discovered how obstructive sleep apnea- affects the gut microbiome in mice and how transplanting gut bacteria from sleep apnea affected mice can cause cardiovascular changes in the recipient mice.
read moreResearchers found metabolytes created by specific gut bacteria during digestion created the link between heart disease and consuming high levels of red meat.
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