News

August 30, 2023
summer 2015

French Documentary Highlights Microbiota Therapy Research at the University of Minnesota

A French Documentary series, The Extraordinary Powers of the Human Body produced by Elephant / 17 Juin Media highlights the University of Minnesota Microbiota Therapeutics Program in Episode 4 "Stomach aches, depression, cancers: the microbiota revolution." View the entire episode or watch the University of Minnesota segment at 1 hour 20 minutes. The segment shares the microbiota transplant therapy used for C. difficile patients, highlights Amanda Kabage's healing experience after receiving a microbiota transplant and the process of creating microbiota therapeutics from donor to capsule.

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August 25, 2023
summer 2015

A team from ASU is bringing hope to families impacted by autism and Pitt-Hopkins syndrome

In this first-ever, double-blind clinical trial, ASU researchers demonstrated that microbiota transplant therapy, which first uses antibiotics to eliminate bad bacteria from the intestines and then replaces it with healthy bacteria, reduces gastrointestinal symptoms and other symptoms in people with autism, as well as in children with Pitt-Hopkins.

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July 6, 2023
summer 2015

University of Minnesota-led study demonstrates safety of microbiota transplant therapy in stem cell transplant and leukemia patients

A study at the University of Minnesota, supported by Achieving Cures Together, indicated Microbiota Transplant Therapy is safe in patients with acute myeloid leukemia and undergoing stem cell transplantation. In the randomized, double blind study, patients enrolled in the active treatment group received microbiota therapeutics after each round of antibiotics. Trial results indicate that patients receiving microbiota transplant therapy had reduced rate of infection compared to patients receiving the placebo, while not statistically significant.

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May 29, 2023
summer 2015

Diversity of the gut microbiota is associated with the severity of depression

A new study indicates that microbial diversity in the gut is closely related to the severity of the major depressive disorder. Compared to healthy individuals, the abundance of Bacteroides species was significantly increased in participants with moderate and severe depression, while Ruminococcus and Eubacterium were depleted mainly in participants with severe depression.

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April 17, 2023
summer 2015

The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice

A recent study demonstrated that the microbiome is altered in patients with Anorexia Nervosa, when compared with healthy individuals. Additionally, when healthy mice received transplanted Anorexia Nervosa stools, initially lost more weight, had slower weight gain and had a higher incidence of appetite suppression genes when compared to mice receiving healthy transplanted stools.

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March 9, 2023
summer 2015

Microscopic organisms in the gut could help manage alcohol use

Achieving Cures Together research partner, Dr. Jasmohan Bajaj at the Virginia Commonwealth University’s School of Medicine, in collaboration with Dr. Alexander Khoruts at the University of Minnesota, is studying the link between microbial health, Advanced Liver Disease and alcohol cravings. An early clinical trial demonstrated the safety of microbiota transplant therapy in patients. A new clinical trial aims to investigate the impact of this therapy in a larger group.

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February 9, 2023
summer 2015

New clinical study is analyzing how gut microbe transplants could help curb alcohol use

ACT research partner, Dr. Jasmohan Bajaj, gastroenterologist and liver specialist, is conducting a new clinical trial to better understand how Intestinal Microbiota Transplants can assist patients in overcoming their addiction to alcohol.

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December 23, 2022
summer 2015

Newly Discovered Species Of Gut Bacteria May Be A Culprit Behind Rheumatoid Arthritis

Findings suggest that previously unknown species of bacteria is the culprit because is found only in the intestines of people with rheumatoid arthritis. We also found that these bacteria can activate specialized immune cells called T cells in people with rheumatoid arthritis. T cells drive inflammatory responses in the body, and have been linked to the development of different autoimmune diseases.

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November 9, 2022
summer 2015

Restoring Gut Microbiome After Antibiotics Could Improve Outcomes for Ovarian Cancer

Antibiotics routinely used in ovarian cancer care indiscriminately kill gut bacteria, leading to faster cancer progression and lower survival rates, according to recent Cleveland Clinic research.

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October 6, 2022
summer 2015

Stanford lab uncovers variation in key infants’ gut microbes

Stanford researchers published findings from their study comparing the infant gut microbiome between industrialized and non-industrialized populations. The discovered that more than 20% of the infant microbiome genome of the Hadza people — one of the last groups of true hunter-gathers in the world — represented novel species that are not present in westernized infants, due to dietary and lifestyle differences.

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