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Explore current research and clinical trials across our primary health focus areas. Use the filters to the right to narrow your search and stay informed on the latest breakthroughs and treatment data.

Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis (ALS) also known as Lou Gehrig’s Disease is a neurodegenerative disorder that affects the nerve cells in your brain and spinal cord affecting muscle control. Almost 5,000 people receive an ALS diagnosis every year. ALS worsens over time and although there is no cure there are treatments to slow the progression of the disease.

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Advanced Liver Disease

Advanced Liver Disease, is also known as End Stage Liver Disease, Chronic Liver Failure, or Decompensated Cirrhosis. In Advanced Liver Disease the liver becomes severely scarred (cirrhosis), which prevents it from functioning properly. It can eventually lead to liver failure.

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Autism

Autism Spectrum Disorder is a neurological and developmental disorder that affects how people interact with others, communicate, learn and behave. Autism can be diagnosed at any age, however is most commonly diagnosed within the first two years of life.

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Cancer: Acute Leukemia

There are over 100 different types of cancer, however, they are typically categorized by where they originate in your body and what tissues they affect. In the United States, an estimated 2.1 million people are diagnosed with cancer every year. Leukemia is a cancer of the blood, distinguished by the rapid growth of abnormal blood cells.

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Cancer: Graft Versus Host Disease

Stem cell transplants are a common treatment for patients with cancer that affect blood cells. Allogeneic stem cells are transplanted from another individual that isn’t the patient or their identical twin. This treatment provides patients with healthy, blood forming stem cells. This treatment is often recommended to patients after receiving high dose chemotherapy or radiation. Some patients develop a complication, Graft Versus Host Disease, after receiving a stem cell transplant.

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Cancer: Immunotherapy Complications*

In the United States, an estimated 2.1 million people are diagnosed with cancer every year. Immunotherapy is a cancer treatment that utilizes your own immune cells to identify cancer cells and destroy them. Different forms of immunotherapy are used to treat cancer including…

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Celiac Disease

Celiac Disease is an autoimmune disease affecting 1 in 133 people or 1% of the population. In Celiac Disease, the immune system reacts to gluten, sometimes causing damage in the small intestine.

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Crohn’s Disease

Crohn’s Disease is a form of Inflammatory Bowel Disease (IBD) that can, if not adequately treated, cause swelling, ulcers and irritation in the digestive tract. Crohn’s Disease most commonly affects the end of the small intestine and beginning of the large intestine, however, inflammation can affect any part of the digestive tract.

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Congestive Heart Failure

Congestive Heart Failure (CHF) is a long-term condition that affects how well your heart does its vital job of pumping blood to the rest of your body. In the United States more than six million people have CHF and it is the leading cause of hospitalization in adults over the age of 65.

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Diverticulitis

Over 50% of adults over the age of 60 have small, bulging pouches in their colon wall, known as diverticula. Three percent of these individuals will develop infection or inflammation in these pouches. Once these pouches have become inflamed the condition is called diverticulitis.

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Food Allergies

Food allergies are immune responses to specific foods that can cause painful and life-threatening reactions. Foods typically driving these responses include peanuts, tree nuts, eggs and cow’s milk, along with other allergens. Ingestion of even a small amount can cause immediate, often severe, reactions. It is estimated that 1 in 10 adults and 1 in 8 children are impacted by this condition.

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Hidradenitis Suppurativa

Hidradenitis Suppurativa (HS) also known as acne inversa is a condition that causes small painful lumps under the skin that affect 1-2% of the population. The lumps heal slowly and can recur causing scarring and tunneling under the skin.

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Kidney Stones

Kidney stones form inside the kidneys and are hard objects, made of salt and minerals that typically pass through the ureter. Kidney stones are very common with 1 in 10 people having them in their lifetime in the United States.

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Multidrug Antibiotic Resistance

Antibiotic Resistance happens when bacteria or fungi become resistant to the antibiotic drugs used to treat infections. These resistant bacteria and fungi, called multidrug resistant organisms or MDROs, are difficult and sometimes impossible to control with currently available antibiotics. Per a CDC report, in the United States more than 2.8 million antimicrobial resistant infections occur every year.

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Primary Sclerosing Cholangitis

Primary Sclerosing Cholangitis (PSC) is a chronic condition where the bile ducts become inflamed, scarred, and can get blocked, preventing bile from flowing properly. PSC is a rare condition that affects about 11 people in every 100,000.

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Pitt-Hopkins Syndrome

Pitt-Hopkins Syndrome is a rare genetic disorder that causes developmental, intellectual, and physical disabilities. Only about 500 people globally are known to have Pitt Hopkins Syndrome.

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Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension (PAH) is a rare type of high blood pressure that impacts the lungs and right side of the heart due to narrowing and blockages of the blood vessels. 500-1000 new cases are diagnosed in the U.S. each year. PAH is more common in women.

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Recurrent C. difficile Infections

Clostridioides difficile (C. difficile) is a type of bacteria that causes an infection in the colon by emitting toxins that damage colonic tissue. C. difficile is common, and infects about half a million people in the United States every year.

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Ulcerative Colitis

Ulcerative Colitis (UC) is a debilitating chronic condition that impacts roughly 900,000 individuals in the United States alone. Ulcerative Colitis is a form of Inflammatory Bowel Disease (IBD) where the immune system causes inflammation and ulcers in the large intestine (colon) and rectum.

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