Gut Microbiome May Alter ALS Progression in Mice
In 1993, amyotrophic lateral sclerosis (ALS) was linked to a genetic mutation in the SOD1 gene. It was a landmark discovery, as were others like it at the time linking neurological diseases to heritable, genetic sources. For example, APO-E, the gene linked to Alzheimer’s disease, was discovered in the same year and the gene for Parkinson’s disease just a few years later.